| Preface | p. xiii |
| Acknowledgments | p. xv |
| Contributors | p. xix |
| Preventive Medicine | |
| Preventing Diabetes: The Diabetes Prevention Program | p. 3 |
| Dietary Approaches to Stop Hypertension (DASH) | p. 9 |
| Aspirin for the Primary Prevention of Cardiovascular Disease: The Physicians' Health Study and the Women's Health Study | p. 15 |
| Postmenopausal Hormone Therapy: The Women's Health Initiative (WHI) | p. 21 |
| The Cochrane Review of Screening Mammography | p. 27 |
| The European Randomized Study of Screening for Prostate Cancer (ERSPC) | p. 33 |
| Screening for Lung Cancer with Low-Dose Computed Tomography versus Chest Radiography: The National Lung Screening Trial (NLST) | p. 39 |
| Endocrinology | |
| Treating Elevated Blood Sugar Levels in Patients with Type 2 Diabetes: The United Kingdom Prospective Diabetes Study (UKPDS) | p. 47 |
| Intensive versus Conservative Blood Sugar Control in Patients with Type 2 Diabetes: The ACCORD Trial | p. 55 |
| Intensive versus Conventional Glycemic Control in Type 1 Diabetes Mellitus: The DCCT Trial | p. 61 |
| Intensive versus Conservative Blood Pressure Control in Patients with Type 2 Diabetes: The ACCORD-BP Trial | p. 67 |
| Hematology and Oncology | |
| Choice of Anticoagulant for Prevention of Recurrent Venous Thromboembolism in Patients with Cancer: The CLOT Trial | p. 75 |
| Vena Cava Filters in the Prevention of Pulmonary Embolism in Patients with Proximal Deep Vein Thrombosis | p. 81 |
| Phase I Study oflmatinib (STI571) in Patients with Chronic Myeloid Leukemia | p. 87 |
| Musculoskeletal Diseases | |
| Magnetic Resonance Imaging for Low Back Pain | p. 95 |
| Early Therapy for Rheumatoid Arthritis: The TICORA Study | p. 101 |
| Nephrology | |
| Revascularization versus Medical Therapy for Renal Artery Stenosis: The ASTRAL Trial | p. 109 |
| Correcting Anemia in Chronic Kidney Disease: The CHOIR Trial | p. 115 |
| Early versus Late Initiation of Dialysis: The IDEAL Study | p. 121 |
| Gastroenterology | |
| Use of IV Albumin in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis | p. 129 |
| Early Use of Transjugular Intrahepatic Portosystemic Shunt (TIPS) in Patients with Cirrhosis and Variceal Bleeding | p. 135 |
| Infectious Diseases | |
| Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department | p. 143 |
| Antibiotic Therapy in Exacerbations of Chronic Obstructive Pulmonary Disease | p. 149 |
| Early versus Delayed Antiretroviral Therapy for Patients with HIV: The NA-ACCORD Study | p. 155 |
| Cardiology | |
| Statins in Healthy Patients with an Elevated C-Reactive Protein: The JUPITER Trial | p. 163 |
| The Scandinavian Simvastatin Survival Study (4S) | p. 169 |
| Choosing First-Line Therapy for Hypertension: The ALLHAT Trial | p. 175 |
| Rate Control versus Rhythm Control for Atrial Fibrillation: The AFFIRM Trial | p. 181 |
| Initial Treatment of Stable Coronary Artery Disease: The COURAGE Trial | p. 187 |
| Early Invasive versus Conservative Management for Unstable Angina or Non-ST-Elevation Myocardial Infarction: The RITA 3 Trial | p. 193 |
| Prophylactic Defibrillator Implantation in Patients with Low Ejection Fraction following Myocardial Infarction: The MADITII Trial | p. 199 |
| Captopril in Patients with Left Ventricular Dysfunction after Myocardial Infarction: The SAVE Trial | p. 205 |
| Spironolactone in Advanced Heart Failure: The RALES Trial | p. 211 |
| The African American Heart Failure Trial (A-HeFT) | p. 217 |
| Intra-Aortic Balloon Support for Myocardial Infarction with Cardiogenic Shock: The IABP-SHOCKII Trial | p. 223 |
| Pulmonary and Critical Care Medicine | |
| Intensive versus Conventional Glucose Control in Critically 111 Patients: The KICE-SUGAR Study | p. 231 |
| Red Cell Transfusion in Critically Ill Patients: The TRICC Trial | p. 237 |
| Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease | p. 243 |
| Low Tidal Volume Ventilation in Acute Respiratory Distress Syndrome/Acute Lung Injury: The ARDSNet Trial | p. 249 |
| Comparison of Routine versus On-Demand Chest Radiographs in Mechanically Ventilated Adults in the Intensive Care Unit | p. 255 |
| Early Goal-Directed Therapy in Sepsis | p. 261 |
| Dopamine versus Norepinephrine in the Treatment of Shock | p. 267 |
| Daily Interruption of Sedative Infusions in Critically Ill Patients Undergoing Mechanical Ventilation | p. 271 |
| A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation | p. 277 |
| Geriatrics and Palliative Care | |
| Behavioral versus Pharmacological Treatment for Insomnia in the Elderly | p. 285 |
| Treatment of Hypertension in the Elderly: The HYVET Trial | p. 291 |
| Use of Feeding Tubes in Patients with Dementia | p. 297 |
| Early Palliative Care in Non-Small-Cell Lung Cancer | p. 303 |
| Mental Health | |
| Initial Treatment of Depression | p. 311 |
| Symptom-Triggered versus Fixed-Dose Therapy for Alcohol Withdrawal | p. 317 |
| Index | p. 323 |
| Table of Contents provided by Ingram. All Rights Reserved. |
